Memory Enhancement
Lion’s mane supports memory and learning. In a clinical trial, older adults with mild cognitive decline who took lion’s mane for 16 weeks showed significant improvements in test scores compared to placebo (Mori et al., Phytother. Res., 2009).
Mental Clarity & Focus
A recent placebo-controlled study found that a single dose of lion’s mane improved cognitive speed and focus in healthy adults (Docherty et al., Nutrients, 2023).
Nerve Regeneration
Lion’s mane contains compounds that stimulate nerve growth. In lab studies, it helped brain cells regrow and reconnect after injury (Journal of Neurochemistry, 2023).
Neuroprotection
It also helps protect the brain from damage. Research shows lion’s mane can reduce inflammation and oxidative stress in the nervous system (Szućko-Kociuba et al., Int. J. Mol. Sci., 2023).
Mood & Stress Support
In a small human trial, lion’s mane reduced symptoms of anxiety and depression in middle-aged women after four weeks (Nagano et al., Biomed. Res., 2010). Researchers believe this may be due to its effect on nerve growth factors.
Gut-Brain Axis Balance
Lion’s mane supports a healthy gut microbiome, boosting beneficial bacteria and reducing gut inflammation. This may positively affect brain function and mood via the gut-brain connection (animal studies).
Immune System Support
Animal studies show lion’s mane can stimulate intestinal immune cells and lower inflammation. A 2024 review highlighted its potential for supporting immune resilience, though more human research is needed.